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Sharma, P, Yan, F, Doronina, V, Escuin-Ordinas, Helena, Ryan, Martin Denis, Brown, Jeremy,
Expression of viral proteins frequently includes non-canonical decoding events (‘recoding’) during translation. ‘2A’ oligopeptides drive one such event, termed ‘stop-carry on’ recoding. Nascent 2A pep...
complete descriptionhttp://hdl.handle.net/10023/2227
Zhou, Linna, Stewart, Gavin, Rideau, Emeline, Westwood, Nicholas James, Smith, Terry K,
Recently, the World Health Organization approved the nifurtimox–eflornithine combination therapy for the treatment of human African trypanosomiasis, renewing interest in nitroheterocycle therapies for...
complete descriptionhttp://europepmc.org/abstract/MED/23281892
Zhou, Linna, Stewart, Gavin, Rideau, Emeline, Westwood, Nicholas James, Smith, Terry K,
Recently, the World Health Organization approved the nifurtimox–eflornithine combination therapy for the treatment of human African trypanosomiasis, renewing interest in nitroheterocycle therapies for...
complete descriptionhttp://hdl.handle.net/10023/3359
Cabrelli, Abigail, Harwood, John, Matthiopoulos, Jason, New, Leslie Frances, Thomas, Len,
The 2005 report of the National Research Council’s ‘Committee on Characterizing Biologically Significant Marine Mammal Behavior’ proposed a framework, which they called PCAD - Population Consequences ...
complete descriptionhttp://hdl.handle.net/10023/2241
Johnson, Mark, Tyack, P L,
Definitive studies on the response of marine mammals to anthropogenic sound are hampered by the short surface time and deep-diving lifestyle of many species. A novel archival tag, called the DTAG, has...
complete descriptionhttp://hdl.handle.net/10023/2594
McClintock, Brett Thomas, King, Ruth, Thomas, Len, Matthiopoulos, Jason, McConnell, Bernie J, Morale...
Recent developments in animal tracking technology have permitted the collection of detailed data on the movement paths of individuals from many species. However, analysis methods for these data have n...
complete descriptionhttp://hdl.handle.net/10023/2605
Zhu, Xiaofeng, Yan, Xuan, Carter, Lester G., Liu, Huanting, Graham, Shirley, Coote, Peter J., Naismi...
The removal of chemically damaged DNA bases such as 3-methyladenine (3-MeA) is an essential process in all living organisms and is catalyzed by the enzyme 3-MeA DNA glycosylase I. A key question is ho...
complete descriptionhttp://hdl.handle.net/10023/3302
Kerry, Philip S., Ayllon, Juan, Taylor, Margaret A., Hass, Claudia, Lewis, Andrew, Garcia-Sastre, Ad...
Influenza A virus NS1 protein is a multifunctional virulence factor consisting of an RNA binding domain (RBD), a short linker, an effector domain (ED), and a C-terminal 'tail'. Although poorly underst...
complete descriptionhttp://hdl.handle.net/10023/2177
Zhou, Linna, Ishizaki, Hironori, Spitzer, Michaela, Taylor, Kerrie, Temperley, Nicholas, Johnson, St...
Understanding how drugs work in vivo is critical for drug design and for maximizing the potential of currently available drugs. 5-nitrofurans are a class of pro-drugs widely used to treat bacterial an...
complete descriptionhttp://hdl.handle.net/10023/3043
Williams, Roderick A. M., Smith, Terry K., Cull, Benjamin, Mottram, Jeremy C., Coombs, Graham H.,
Macroautophagy has been shown to be important for the cellular remodelling required for Leishmania differentiation. We now demonstrate that L. major contains a functional ATG12-ATG5 conjugation system...
complete descriptionhttp://hdl.handle.net/10023/3051