Chan, Joyce, M. Eng. Massachusetts Institute of Technology,
This study aims to investigate the relationships between growth parameters (agitation, glycerol concentration, salt concentration) and responses (biomass, growth rate, protein expression), by a 3-fact...
complete descriptionhttp://hdl.handle.net/1721.1/33872
Awasthi, Samir,
Cancer science is a heavily researched and rapidly changing field. Cutting edge research consistently reveals unique features of tumors that can be exploited for treatment. For example, it is well kno...
complete descriptionhttp://hdl.handle.net/1721.1/39922
Varner, Johanna (Johanna M.),
Neurodegenerative diseases typically affect a limited number of specific neuronal subtypes, and the death of these neurons causes permanent loss of a specific motor function. Efforts to restore functi...
complete descriptionhttp://hdl.handle.net/1721.1/39919
Alkhairy, Samiya Ashraf,
Purpose: This research develops a modeling approach and an implementation toolset to simulate reticular lamina displacement in response to excitation at the ear canal and to characterize the cochlear ...
complete descriptionhttp://hdl.handle.net/1721.1/67201
Bouhenguel, Jason T,
One and a half million new cancer cases are reported each year in the United States. Despite this overwhelming burden of disease, current preventative treatments and early detection techniques are ina...
complete descriptionhttp://hdl.handle.net/1721.1/62390
Wu, Jonathan (Jonathan G.),
Isolated hepatocytes removed from their microenvironment soon lose their hepatospecific functions when cultured. Highly oxygen-demanding hepatocytes are commonly maintained under oxygen-deficient cult...
complete descriptionhttp://hdl.handle.net/1721.1/39918
Tentner, Andrea R. (Andrea Ruth),
Following exposure to DNA damage, cells initiate a stress response involving multiple protein kinase signaling cascades. The DNA damage response results in one of several possible cell-fate decisions,...
complete descriptionhttp://hdl.handle.net/1721.1/34561
Eavarone, David A. (David Alan),
Anti-angiogenic therapy offers many benefits over traditional cytotoxic chemotherapy including fewer toxic side effects and the reduced development of drug resistance. Anti-angiogenics alone have not ...
complete descriptionhttp://hdl.handle.net/1721.1/34158
Swaminathan, Krishnakumar,
Objectives: 1) To perform a quantitative comparison of proteins released to media on combination with cytokine (IL-1[beta[ or TNF-[alpha]) and Injury as compared to either treatment alone, and to thus...
complete descriptionhttp://hdl.handle.net/1721.1/67209
Sefta, Meriem,
Agents that damage our DNA are omnipresent in our environment and inside our cells themselves. Left unrepaired, DNA damage can lead to premature aging, neurodegeneration and cancer. Humans have thus e...
complete descriptionhttp://hdl.handle.net/1721.1/71472