Recent queries:
Petry, Neil,
Radiopharmaceuticals are radioactive drugs that are used in nuclear medicine practice for diagnosis and treatment of disease. Nuclear pharmacy practice is a patient-oriented pharmaceutical service tha...
complete descriptionweight 5577http://hdl.handle.net/2027.42/69138
Dua, Rajesh K. Woodard, Ronald W. Flynn, Gordon L. Stinchcomb, Audra L. Imoto, Hirofumi Paliwal, Anu...
Purpose . Homologous 3-alkyl-ester prodrugs (C 2 to C 4 ) of buprenorphine with decreased crystallinity have been synthesized and evaluated for transdermal delivery commensurate with opioid dependence...
complete descriptionweight 5574http://hdl.handle.net/2027.42/41449
Lennernäs, Hans Shah, Vinod P. Barnett, Jeffrey L. Lesko, Lawrence J. Rhie, Julie K. Welage, Lynda S...
Purpose . To determine the human jejunal permeabilities of compounds utilizing different transport mechanisms using a regional perfusion approach and to establish a standard procedure for determining ...
complete descriptionweight 5574http://hdl.handle.net/2027.42/41460
Putcha, Lakshmi Amidon, Gregory E. Wald, Randy J. Barnett, Jeffrey L. Amidon, Gordon L. Rhie, Julie ...
Purpose . The objective of this study was to evaluate drug marker absorption in relation to the gastric emptying (GE) of 0.7 mm and 3.6 mm enteric coated pellets as a function of viscosity and the und...
complete descriptionweight 5574http://hdl.handle.net/2027.42/41465
Oh, Doo-Man Rhie, Julie K. Smith, Philip L. Lee, Chao-Pin Amidon1, Gordon L. Sadee, Wolfgang Han, Hy...
Purpose . General use of nucleoside analogues in the treatment of viral infections and cancer is often limited by poor oral absorption. Valacyclovir, a water soluble amino acid ester prodrug of acyclo...
complete descriptionweight 5574http://hdl.handle.net/2027.42/41466
Berger, Urs V. Yang, Tianxin Hediger, Matthias A. Pavlova, Anna Smith, David E. Schnermann, Jürgen B...
Purpose . To define the tubular localization and tissue distribution of PEPT1 (low-affinity, high-capacity transporter) and PEPT2 (high-affinity, low-capacity transporter) in rat kidney.
weight 5574http://hdl.handle.net/2027.42/41467
Zhou, Simon Yuji Liu, Guangyu Piyapolrungroj, Nusara Zimmermann, Ellen M. Li, Cheng Fleisher, David ...
Purpose . Isolating the relative contributions of parallel transcellular and paracellular transport to the intestinal absorption of small hydrophilic molecules has proven experimentally challenging. I...
complete descriptionweight 5574http://hdl.handle.net/2027.42/41472
Williamson, Rufus M. Amidon, Gordon L. Stewart, Barbra H. Surendran, Narayanan Oh, Doo-Man Sadee, Wo...
Purpose . The objective of this research was to investigate the substrate specificity of large neutral amino acid carrier (LNAA) and di/tripeptide (hPEPTl) transporters with respect to PD 158473, an N...
complete descriptionweight 5574http://hdl.handle.net/2027.42/41475
Zhu, Tong Steel, Angela Smith, David E. Chen, Xing-Zhen Hediger, Matthias A.,
Purpose . To examine the mechanism of inhibition of glycylsarcosine(GlySar) transport by quinapril and enalapril, and whether or notangiotensin converting enzyme (ACE) inhibitors are transported by PE...
complete descriptionweight 5574http://hdl.handle.net/2027.42/41482
Raczka, Ewa Baker, James R. Mulé, James Majoros, Istvan Myc, Andrzej Patri, Anil K. Quintana, Antoni...
Purpose . We sought to develop nanoscale drug delivery materials that would allow targeted intracellular delivery while having an imaging capability for tracking uptake of the material. A complex nano...
complete descriptionweight 5574http://hdl.handle.net/2027.42/41493
