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Molecular, Cellular and Developmental Biology

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1. Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxofylline

Strieter, Robert M. Remick, Daniel G. Ward, Peter A. Spengler, Robert N. Lynch III, J.P. Larrick, Ja...

Tumor necrosis factor-alpha (TNF), a mononuclear phagocyte (MO)-derived peptide, is increasingly being recognized for its pleomorphic immunologic effects. A number of investigations have demonstrated ...

complete descriptionweight 9570

2. Studies of the Molecular Mechanism and Signaling Regulation of Autophagy in Saccharomyces Cerevisiae.

Yang, Zhifen,

Autophagy is a highly conserved cellular degradation process in which portions of cytosol and organelles are sequestered into a double-membrane vesicle, an autophagosome, and delivered into a degradat...

complete descriptionweight 9565

3. Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp

Shreffler, Donald C. Hansen, T. H. Krasteff, T. N.,

A radial immunodiffusion assay for quantitation of the Ss and Slp serum antigens is described. Significant differences between the mean serum concentrations of Ss and Slp were found among various inbr...

complete descriptionweight 9562

4. Aging and immune function: Cellular and biochemical analyses

Miller, Richard A.,

Recent progress on the cellular and molecular basis for T cell dysfunction in aged mice is reviewed, with emphasis on defects in calcium signal generation and protein kinase function. The accumulation...

complete descriptionweight 9562

6. Pharmacology, distribution, cellular localization, and development of GABAB binding in rodent cerebellum

Turgeon, Sarah M. Albin, Roger L.,

Quantitative receptor autoradiography using [3H]GABA under selective conditions was used to characterize the pharmacology, distribution, cellular localization, and development of GABAB binding sites i...

complete descriptionweight 8570

7. Histamine and cis-urocanic acid augment tumor necrosis factor-alpha mediated induction of keratinocyte intercellular adhesion molecule-1 expression

Mitra, Raj S. Shimizu, Yoji Nickoloff, Brian J.,

Early cellular and molecular events in inflamed skin include the active participation of epidermal keratinocytes (KCs) and dermal mast cells which can produce diffusible mediators such as tumor necros...

complete descriptionweight 8570

8. A retinoic acid-inducible skin-specific gene (RIS-1/psoriasin): molecular cloning and analysis of gene expression in human skin in vivo and cultured skin cells in vitro

Tavakkol, Amir Zouboulis, Christos C. Duell, Elizabeth A. Voorhees, John J.,

A retinoic acid (RA) inducible skin-specific gene transcript (RIS-1) was isolated by differential hybridization screening of a RA-treated human skin cDNA library. The library was constructed from pool...

complete descriptionweight 8568

9. Expression of Corticotropin-Releasing Hormone Transgenes in Neurons of Adult and Developing Mice

Keegan, Catherine E. Karolyi, I. Jill Knapp, Lauren T. Bourbonais, Francis J. Camper, Sally A. Seash...

The DNA sequences important for cell-specific expression and developmental regulation of corticotropin-releasing hormone (CRH) were analyzed in transgenic mice. A construct containing 0.5 kb of CRH 5'...

complete descriptionweight 8568

10. Applications of Functional Genomics in Studies of Yeast Signaling Networks and Genome Structure.

Ma, Jun,

Genomic and proteomic approaches combined with traditional methods in molecular and cell biology have been applied to the model organism Saccharomyces cerevisiae, resulting in the identification of li...

complete descriptionweight 8567
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